Measles, what you should know.

[BIG_DADDY]

Most of you have heard of the recent measles outbreak mostly linked to Disneyland over the holidays. As of January 27th, a total of 73 cases of measles have been confirmed in the state of California, 48 of which are linked to those who recently visited Disneyland. There are 9 confirmed cases in the Bay Area. Alameda County has 5 cases, 4 of which are probably linked to Disneyland. There are 2 cases each in San Mateo and Santa Clara counties, none of which are directly linked to Disneyland.

Since news of the outbreak, I think it is important to separate fact from the fear that is circulating in the media.

What is measles?

In order to understand what the fear is about, the first thing to understand is what exactly measles is. Measles, also called rubeola, is a highly-contagious viral infection. It is airborne, meaning that it is transmitted by droplets from an infected person’s nose and throat, such as during coughing and sneezing. These droplets can survive in the air and on objects and surfaces for up to 2 hours, but are rapidly killed by heat, light (UV and visible), detergents and organic solvents. Once exposed, the measles virus begins to multiply in the nasal cavity. Two to three days later, the virus continues to replicate and spread from the nasopharynx to the lymphatic system, and eventually to the respiratory tract and other organs. It typically takes 10-12 days for a person to develop symptoms after exposure to measles (the incubation period), but this may be as short as 7 or as long as 18 days.

Takeaway: If the viral replication can be stopped at the time of exposure, this may help prevent actual infection. Consider daily nasal irrigation with Xlear saline nasal spray, neti pot, Neilmed sinus rinse or equivalent. The measles virus is easily inactivated – wash your hands frequently and before you touch your face or eat.

Initial symptoms mimic influenza symptoms, with a fever which can rise as high as 103°F-105°F. This is followed by coryza (runny nose), cough, and conjunctivitis (pinkeye) – the 3 "C’s". With our concurrent flu season in full force, it can be very challenging to differentiate initial measles symptoms with flu symptoms. However, it is during these early stages of measles that we can see what are called "Koplik spots", which are considered definitive for measles. These are discrete white spots on a red base on the inner cheek that appear 1-2 days before, and last 1-2 days after the measles rash develops, and unfortunately are usually gone by the time patients present to a clinic with a rash. The measles rash will develop 2-4 days after upper respiratory symptoms appear and last for approximately 5-6 days. The rash is red and blotchy and some spots may merge, typically starting on the face and moving down the body to the hands and feet, and disappears in that same order. The rash is generally not itchy.

An infected person is contagious for about 4 days before symptoms start, and until 4 days after the rash develops. The secondary "attack rate", or the likelihood of an unprotected person actually getting the infection if they are exposed during this period, is over 90%. The attack rate is highest the younger you are – 94% for children 1 to 4 years of age, and 91% for children 5 to 14 years of age.

The prognosis for measles is generally good. Complications are more likely to occur in children younger than 5 years of age and adults over 20 years of age, and in individuals with vitamin A deficiency, malnutrition, and immunodeficiency. The risk of death is approximately 1-2 per 1,000 cases – with the highest fatality rates seen in children less than 5 years, and in particular those infants aged 4-12 months. Common relatively minor complications include diarrhea in 8%, ear infections in 7% and pneumonia in 6%. While rare, encephalitis (brain infection) can occur in about 1 per 1,000 cases of measles, with an approximately 15% fatality rate, and 25% who will continue to have some residual neurologic damage. While very rare, with anywhere from 1-22 per 100,000 cases, subacute sclerosing panencephalitis (SSPE) is a very serious complication of measles. This is a fatal, progressive degenerative neurologic disease that occurs unpredictably, 7-10 years after a seemingly full recovery from the initial measles infection, resulting eventually in behavioral and cognitive changes, seizures, coma, and death. The risk of SSPE may be higher for patients who contract measles before 2 years of age.

Treatment for measles is supportive. Several studies have shown that high-dose vitamin A may be useful in reducing complications and death from measles, especially in those patients who are deficient in vitamin A. The World Health Organization recommends high-dose vitamin A for all children with acute measles, regardless of vitamin A status. High doses of vitamin A for prolonged periods may have associated toxicity. However, this 2-day protocol is very unlikely to lead to toxicity in the short term. The protocol is as follows – Vitamin A is administered once daily for 2 days at the following doses:
• 50,000 IU for infants aged less than 6 months
• 100,000 IU for infants aged 6–11 months
• 200,000 IU for children aged 12 months and older
Takeaway: Measles is generally a self-limiting disease in most healthy children. Complications are more likely to be severe in individuals who are deficient in vitamin A and malnourished in general. Eat plenty of fruits and vegetables. Avoid sugars and processed foods. Supplement with vitamin D as one of the most important ways to boost your immune system through the winter. Ensure that you and your children get at least the recommended daily allowance of vitamin A. Remember that cod liver oil is a great source of vitamin A AND vitamin D. While optimal daily supplementation levels are not entirely clear, the following are the "tolerable upper intake levels" of vitamin A in international units (IU) as set forth by the Food and Nutrition Board:
Life Stage Upper Limit
Birth to 12 months 2,000 IU
Children 1–3 years 2,000 IU
Children 4–8 years 3,000 IU
Children 9–13 years 5,667 IU
Teens 14–18 years 9,333 IU
Adults 19 years and older 10,000 IU

Antipyretics (fever reducers such as Tylenol and Motrin) have been found in many studies to prolong the course of viral illnesses, like chickenpox and measles. Studies have linked the use of antipyretics for the fever with measles to a significantly higher risk of prolonged illness, complications, and mortality. In fact, one study of children in Ghana during a measles outbreak found higher survival rates in children who had higher fevers and more severe rashes.

Takeaway: Fever is the body’s natural and useful response to infection. Do not succumb to fever phobia. In general, limit antipyretics for when your child is uncomfortable enough that it interferes with staying hydrated or getting adequate sleep. There are many homeopathic medicines that can be used to help the body naturally regulate its fever response. Please consult with your doctor for the most appropriate natural and/or conventional medicines to use should your child develop a fever.

What about the MMR vaccine?

The only vaccination against measles that is currently available is the MMR (measles-mumps-rubella) vaccine, and MMRV (MMR plus chickenpox) vaccine. The measles vaccine is no longer available as a separate single-strain vaccine. The MMR vaccine is a "live-virus" vaccine, which means that you are receiving a live, but weakened version of the viruses to create a mild infection with subsequent antibody response and protection. MMR is typically first given between 12-18 months of age, with a second MMR given between 4-6 years of age. After the first dose, approximately 95% of children vaccinated at 12 months of age, and approximately 98% of children vaccinated at 15 months of age will develop protective measles antibodies. Even one dose can be highly effective in preventing measles. But a second dose (technically not a booster) at 4-6 years of age is recommended to capture the 2-5% of children who did not respond to the first vaccine. This second dose may be administered as soon as 4 weeks after the first dose should there be a question as to efficacy. For children who have had their first MMR but are not yet at the recommended age for their second dose, options include receiving their second MMR before they are 4-6 years of age, or doing bloodwork to check for protective antibody levels (measles titers). Adults do not need a booster if they received a measles vaccine after 1968. For adults who are not sure that they’ve been vaccinated, options include checking measles titers or receiving an MMR vaccine. In outbreaks, the CDC may recommend that children as young as 6 months of age receive the MMR. Children between 6-12 months of age are less likely to respond to the vaccine and make appropriate antibodies, and are still recommended to receive the recommended 2 doses at 12-18 months and 4-6 years. There is evidence that vaccination within 72 hours of exposure to measles may prevent disease in those who are unprotected.

The vaccination status is known for 39 of the California patients who have contracted measles. Of these 39 patients, 32 were unvaccinated and 7 were fully vaccinated.

Takeaway: Even one dose of the MMR appears to be very effective in providing immunity against measles. However, no vaccine is 100% effective. A second dose may be required for some patients, especially those who received their first vaccine at less than 12 months of age. Post-exposure vaccination within 72 hours may be effective. Ensuring adequate nutrition and vitamin A as above continue to be important for all individuals regardless of vaccination status.

Because it is a live-virus vaccine, the MMR is not to be given to pregnant women or to individuals who are immunocompromised or are receiving immunosuppressant therapies. It is also contraindicated in individuals with a history of severe allergic reaction to gelatin, neomycin or any other component of the vaccine. Precautions should be taken in patients with moderate or severe illness with or without fever, or a personal or family history of febrile seizures. The measles virus used in the vaccine is grown in chicken embryo culture, but anaphylactic egg allergy is not considered a contraindication to the vaccine.

Takeaway: There are individuals for whom the MMR vaccine is not an option. Unprotected individuals who cannot receive the MMR vaccine (infants, pregnant women, immunocompromised individuals) may rely on "herd immunity", or high vaccination rates in the community, for their protection.

What are the possible adverse reactions to the MMR? Just as no vaccine is 100% effective, no vaccine is 100% risk-free. The most common adverse reaction is typically due to the replication of the measles vaccine virus to induce a mild illness. This typically occurs 5-12 days after receiving the vaccine, and can include fever for 1-2 days and a rash. Joint pains are seen in 25% of susceptible adult women, due to the rubella component. The risk of febrile seizures increases 3-fold 8-14 days after the MMR vaccine, but is still relatively low. Anaphylaxis and thrombocytopenia (low platelet count) are other rare complications. There may be a link between the measles vaccine and SSPE of about 1 case per million vaccine doses, which is significantly lower than the risk of SSPE from a primary measles infection.

Of biggest concern for many parents is the proposed link between vaccines and autism, and in particular between the MMR vaccine and autism. While the media and common public opinion are quick to say that the link between vaccines and autism has been absolutely disproved, they have not done their due diligence research. The National Vaccine Injury Compensation Program (VICP, also called “vaccine court”), established by Congress in 1986, was created to provide a “no-fault” mechanism to compensate individuals found to be injured by vaccines. By 2010, the VICP had awarded nearly $2 billion to individuals who had suffered vaccine injuries. It has awarded at least 4 families millions of dollars after finding that their children had suffered from brain damage (encephalitis) caused by the MMR and other vaccines, which then resulted in regressive autistic symptoms. Since its inception, the vaccine court has awarded money judgments, often to the tune of millions of taxpayer dollars, to 1,322 families whose children were found to have suffered brain damage from vaccines. In August of 2014, a top research scientist whistleblower at the CDC released information that the CDC had manipulated data in an MMR and autism study to obscure the higher incidence of autism found in African-American boys who received the MMR vaccine before 36 months of age.

That being said, it remains that most children will not develop significant adverse reactions to the MMR vaccine. Is there any way to predict which children may be more vulnerable to vaccine reactions, or any way to prevent these reactions from occurring? In taking a closer look at the cases that were won in vaccine court, one case was won on the grounds that the MMR caused autism by aggravating an underlying mitochondrial disorder, and another case was won on the grounds that the MMR caused autism by triggering an autoimmune reaction called Acute Disseminated Encephalomyelitis (ADEM) which caused irreparable brain inflammation. One might conjecture then, that a child who has a suspected mitochondrial dysfunction, or who has a strong family history of autoimmune illness, may be more at risk for these rare, albeit devastating, reactions. What are possible signs of mitochondrial dysfunction – low muscle tone, easy fatigue/poor endurance, delayed developmental milestones, regressions with illness, and lab evidence (including high serum lactate, high serum CK, high AST, low serum carnitine).

A possible mitochondrial dysfunction and/or family history of autoimmune illness are not absolute contraindications to the MMR vaccine. They are, however, precautions. The risk of adverse vaccine reactions must be weighed against the risk of actual disease. In 2000, measles was thought to be mostly eliminated in the US. Measles is now on the rise, and hopefully will not reach the epidemic proportions it has in Europe. Now that the measles infection rate may potentially be climbing, this risk must be taken into account. Likewise, the community benefit of herd protection for infants and immunocompromised individuals must also be considered. These are all considerations that each parent must take into account for their own children. For children who may have mitochondrial dysfunction, or a family history of autoimmune illness, there are supplements that may help to reduce and prevent potential adverse reactions from the MMR vaccine while still enabling the measles protection that it can afford.

Takeaway: Most children will not experience adverse reactions to the MMR vaccine. Given the increasing prevalence of measles, consideration should be given to getting vaccinated, either now or within 72 hours of known exposure. However, if there is a possibility of mitochondrial dysfunction, or strong family history of autoimmune illness or neurodegenerative disease you may want to reconsider. Supplements to help reduce the risk of adverse reactions. These may include carnitine, coQ10, milk thistle, vitamin A, homeopathic Thuja, and others.



Good information on Hib and MMR.
Most of you have heard of the recent measles outbreak mostly linked to Disneyland over the holidays. As of this writing, a total of 73 cases of measles have been confirmed in the state of California, 48 of which are linked to those who recently visited Disneyland. There are 9 confirmed cases in the Bay Area. Alameda County has 5 cases, 4 of which are probably linked to Disneyland. There are 2 cases each in San Mateo and Santa Clara counties, none of which are directly linked to Disneyland.

Since news of the outbreak, I have received numerous questions about measles and the MMR vaccine. My goal in writing this newsletter now is to hopefully shed some light on this measles epidemic, and to separate fact from the fear that is circulating in the media.

What is measles?

In order to understand what the fear is about, the first thing to understand is what exactly measles is. Measles, also called rubeola, is a highly-contagious viral infection. It is airborne, meaning that it is transmitted by droplets from an infected person’s nose and throat, such as during coughing and sneezing. These droplets can survive in the air and on objects and surfaces for up to 2 hours, but are rapidly killed by heat, light (UV and visible), detergents and organic solvents. Once exposed, the measles virus begins to multiply in the nasal cavity. Two to three days later, the virus continues to replicate and spread from the nasopharynx to the lymphatic system, and eventually to the respiratory tract and other organs. It typically takes 10-12 days for a person to develop symptoms after exposure to measles (the incubation period), but this may be as short as 7 or as long as 18 days.

Takeaway: If the viral replication can be stopped at the time of exposure, this may help prevent actual infection. Consider daily nasal irrigation with Xlear saline nasal spray, neti pot, Neilmed sinus rinse or equivalent. The measles virus is easily inactivated – wash your hands frequently and before you touch your face or eat.

Initial symptoms mimic influenza symptoms, with a fever which can rise as high as 103°F-105°F. This is followed by coryza (runny nose), cough, and conjunctivitis (pinkeye) – the 3 "C’s". With our concurrent flu season in full force, it can be very challenging to differentiate initial measles symptoms with flu symptoms. However, it is during these early stages of measles that we can see what are called "Koplik spots", which are considered definitive for measles. These are discrete white spots on a red base on the inner cheek that appear 1-2 days before, and last 1-2 days after the measles rash develops, and unfortunately are usually gone by the time patients present to a clinic with a rash. The measles rash will develop 2-4 days after upper respiratory symptoms appear and last for approximately 5-6 days. The rash is red and blotchy and some spots may merge, typically starting on the face and moving down the body to the hands and feet, and disappears in that same order. The rash is generally not itchy.

An infected person is contagious for about 4 days before symptoms start, and until 4 days after the rash develops. The secondary "attack rate", or the likelihood of an unprotected person actually getting the infection if they are exposed during this period, is over 90%. The attack rate is highest the younger you are – 94% for children 1 to 4 years of age, and 91% for children 5 to 14 years of age.

The prognosis for measles is generally good. Complications are more likely to occur in children younger than 5 years of age and adults over 20 years of age, and in individuals with vitamin A deficiency, malnutrition, and immunodeficiency. The risk of death is approximately 1-2 per 1,000 cases – with the highest fatality rates seen in children less than 5 years, and in particular those infants aged 4-12 months. Common relatively minor complications include diarrhea in 8%, ear infections in 7% and pneumonia in 6%. While rare, encephalitis (brain infection) can occur in about 1 per 1,000 cases of measles, with an approximately 15% fatality rate, and 25% who will continue to have some residual neurologic damage. While very rare, with anywhere from 1-22 per 100,000 cases, subacute sclerosing panencephalitis (SSPE) is a very serious complication of measles. This is a fatal, progressive degenerative neurologic disease that occurs unpredictably, 7-10 years after a seemingly full recovery from the initial measles infection, resulting eventually in behavioral and cognitive changes, seizures, coma, and death. The risk of SSPE may be higher for patients who contract measles before 2 years of age.

Treatment for measles is supportive. Several studies have shown that high-dose vitamin A may be useful in reducing complications and death from measles, especially in those patients who are deficient in vitamin A. The World Health Organization recommends high-dose vitamin A for all children with acute measles, regardless of vitamin A status. High doses of vitamin A for prolonged periods may have associated toxicity. However, this 2-day protocol is very unlikely to lead to toxicity in the short term. The protocol is as follows – Vitamin A is administered once daily for 2 days at the following doses:
• 50,000 IU for infants aged less than 6 months
• 100,000 IU for infants aged 6–11 months
• 200,000 IU for children aged 12 months and older
Takeaway: Measles is generally a self-limiting disease in most healthy children. Complications are more likely to be severe in individuals who are deficient in vitamin A and malnourished in general. Eat plenty of fruits and vegetables. Avoid sugars and processed foods. Supplement with vitamin D as one of the most important ways to boost your immune system through the winter. Ensure that you and your children get at least the recommended daily allowance of vitamin A. Remember that cod liver oil is a great source of vitamin A AND vitamin D. While optimal daily supplementation levels are not entirely clear, the following are the "tolerable upper intake levels" of vitamin A in international units (IU) as set forth by the Food and Nutrition Board:
Life Stage Upper Limit
Birth to 12 months 2,000 IU
Children 1–3 years 2,000 IU
Children 4–8 years 3,000 IU
Children 9–13 years 5,667 IU
Teens 14–18 years 9,333 IU
Adults 19 years and older 10,000 IU

Antipyretics (fever reducers such as Tylenol and Motrin) have been found in many studies to prolong the course of viral illnesses, like chickenpox and measles. Studies have linked the use of antipyretics for the fever with measles to a significantly higher risk of prolonged illness, complications, and mortality. In fact, one study of children in Ghana during a measles outbreak found higher survival rates in children who had higher fevers and more severe rashes.

Takeaway: Fever is the body’s natural and useful response to infection. Do not succumb to fever phobia. In general, limit antipyretics for when your child is uncomfortable enough that it interferes with staying hydrated or getting adequate sleep. There are many homeopathic medicines that can be used to help the body naturally regulate its fever response. Please consult with your doctor for the most appropriate natural and/or conventional medicines to use should your child develop a fever.

What about the MMR vaccine?

The only vaccination against measles that is currently available is the MMR (measles-mumps-rubella) vaccine, and MMRV (MMR plus chickenpox) vaccine. The measles vaccine is no longer available as a separate single-strain vaccine. The MMR vaccine is a "live-virus" vaccine, which means that you are receiving a live, but weakened version of the viruses to create a mild infection with subsequent antibody response and protection. MMR is typically first given between 12-18 months of age, with a second MMR given between 4-6 years of age. After the first dose, approximately 95% of children vaccinated at 12 months of age, and approximately 98% of children vaccinated at 15 months of age will develop protective measles antibodies. Even one dose can be highly effective in preventing measles. But a second dose (technically not a booster) at 4-6 years of age is recommended to capture the 2-5% of children who did not respond to the first vaccine. This second dose may be administered as soon as 4 weeks after the first dose should there be a question as to efficacy. For children who have had their first MMR but are not yet at the recommended age for their second dose, options include receiving their second MMR before they are 4-6 years of age, or doing bloodwork to check for protective antibody levels (measles titers). Adults do not need a booster if they received a measles vaccine after 1968. For adults who are not sure that they’ve been vaccinated, options include checking measles titers or receiving an MMR vaccine. In outbreaks, the CDC may recommend that children as young as 6 months of age receive the MMR. Children between 6-12 months of age are less likely to respond to the vaccine and make appropriate antibodies, and are still recommended to receive the recommended 2 doses at 12-18 months and 4-6 years. There is evidence that vaccination within 72 hours of exposure to measles may prevent disease in those who are unprotected.

The vaccination status is known for 39 of the California patients who have contracted measles. Of these 39 patients, 32 were unvaccinated and 7 were fully vaccinated.

Takeaway: Even one dose of the MMR appears to be very effective in providing immunity against measles. However, no vaccine is 100% effective. A second dose may be required for some patients, especially those who received their first vaccine at less than 12 months of age. Post-exposure vaccination within 72 hours may be effective. Ensuring adequate nutrition and vitamin A as above continue to be important for all individuals regardless of vaccination status.

Because it is a live-virus vaccine, the MMR is not to be given to pregnant women or to individuals who are immunocompromised or are receiving immunosuppressant therapies. It is also contraindicated in individuals with a history of severe allergic reaction to gelatin, neomycin or any other component of the vaccine. Precautions should be taken in patients with moderate or severe illness with or without fever, or a personal or family history of febrile seizures. The measles virus used in the vaccine is grown in chicken embryo culture, but anaphylactic egg allergy is not considered a contraindication to the vaccine.

Takeaway: There are individuals for whom the MMR vaccine is not an option. Unprotected individuals who cannot receive the MMR vaccine (infants, pregnant women, immunocompromised individuals) may rely on "herd immunity", or high vaccination rates in the community, for their protection.

What are the possible adverse reactions to the MMR? Just as no vaccine is 100% effective, no vaccine is 100% risk-free. The most common adverse reaction is typically due to the replication of the measles vaccine virus to induce a mild illness. This typically occurs 5-12 days after receiving the vaccine, and can include fever for 1-2 days and a rash. Joint pains are seen in 25% of susceptible adult women, due to the rubella component. The risk of febrile seizures increases 3-fold 8-14 days after the MMR vaccine, but is still relatively low. Anaphylaxis and thrombocytopenia (low platelet count) are other rare complications. There may be a link between the measles vaccine and SSPE of about 1 case per million vaccine doses, which is significantly lower than the risk of SSPE from a primary measles infection.

Of biggest concern for many parents is the proposed link between vaccines and autism, and in particular between the MMR vaccine and autism. While the media and common public opinion are quick to say that the link between vaccines and autism has been absolutely disproved, they have not done their due diligence research. The National Vaccine Injury Compensation Program (VICP, also called “vaccine court”), established by Congress in 1986, was created to provide a “no-fault” mechanism to compensate individuals found to be injured by vaccines. By 2010, the VICP had awarded nearly $2 billion to individuals who had suffered vaccine injuries. It has awarded at least 4 families millions of dollars after finding that their children had suffered from brain damage (encephalitis) caused by the MMR and other vaccines, which then resulted in regressive autistic symptoms. Since its inception, the vaccine court has awarded money judgments, often to the tune of millions of taxpayer dollars, to 1,322 families whose children were found to have suffered brain damage from vaccines. In August of 2014, a top research scientist whistleblower at the CDC released information that the CDC had manipulated data in an MMR and autism study to obscure the higher incidence of autism found in African-American boys who received the MMR vaccine before 36 months of age.

That being said, it remains that most children will not develop significant adverse reactions to the MMR vaccine. Is there any way to predict which children may be more vulnerable to vaccine reactions, or any way to prevent these reactions from occurring? In taking a closer look at the cases that were won in vaccine court, one case was won on the grounds that the MMR caused autism by aggravating an underlying mitochondrial disorder, and another case was won on the grounds that the MMR caused autism by triggering an autoimmune reaction called Acute Disseminated Encephalomyelitis (ADEM) which caused irreparable brain inflammation. One might conjecture then, that a child who has a suspected mitochondrial dysfunction, or who has a strong family history of autoimmune illness, may be more at risk for these rare, albeit devastating, reactions. What are possible signs of mitochondrial dysfunction – low muscle tone, easy fatigue/poor endurance, delayed developmental milestones, regressions with illness, and lab evidence (including high serum lactate, high serum CK, high AST, low serum carnitine).

A possible mitochondrial dysfunction and/or family history of autoimmune illness are not absolute contraindications to the MMR vaccine. They are, however, precautions. The risk of adverse vaccine reactions must be weighed against the risk of actual disease. In 2000, measles was thought to be mostly eliminated in the US. Measles is now on the rise, and hopefully will not reach the epidemic proportions it has in Europe. Now that the measles infection rate may potentially be climbing, this risk must be taken into account. Likewise, the community benefit of herd protection for infants and immunocompromised individuals must also be considered. These are all considerations that each parent must take into account for their own children. For children who may have mitochondrial dysfunction, or a family history of autoimmune illness, there are supplements that may help to reduce and prevent potential adverse reactions from the MMR vaccine while still enabling the measles protection that it can afford.

Takeaway: Most children will not experience adverse reactions to the MMR vaccine. Given the increasing prevalence of measles, consideration should be given to getting vaccinated, either now or within 72 hours of known exposure. However, if there is a possibility of mitochondrial dysfunction, or strong family history of autoimmune illness or neurodegenerative disease, Dr. Song and Dr. Ruiz are available to consult with you on supplements to help reduce the risk of adverse reactions. These may include carnitine, coQ10, milk thistle, vitamin A, homeopathic Thuja, and others.

[Fat Elvis]

Originally Posted by DaFace

Probably somewhere above the "g" in "nothing." The difference between me and anti-vaxxers is that I rely on the people to the right of me to draw conclusions rather than relying on people to the left.

Why rely on doctors and scientists for knowledge when you have a Playboy bunny with all the answers?

[lewdog]

I was hoping to come in here and find the anti-vaccinators dead, which is what they should get.

This ****ing sucks.

[Fish]

Heh...

[Eleazar]

Is the Measles Vaccine Worthwhile?
Andrew Weil, M.D.
February 10, 2015


If you view measles as merely an uncomfortable, annoying, or trivial disease of childhood, you should be aware of its history. Its complications can be devastating - about one patient in 10 will develop an ear infection (otitis media) and one in 15 will get pneumonia, which can be serious and is life-threatening in some cases. About one measles patient in 1,000 contracts encephalitis, an inflammation of the brain that causes nausea and vomiting, seizures and sometimes coma and death. Measles can also cause deafness. Cases occurring in pregnant women can lead to miscarriage and low birth-weight babies.

The virus that causes measles is so easily spread that 90 percent of those exposed will get sick. What's more, the virus can linger in the air after an infected person leaves the scene and continue to infect others for up to two hours. Children (and adults) are safe only if they've been vaccinated or have already had measles.

Approximately 30 million to 40 million cases of measles occur worldwide each year, resulting in nearly a million deaths and incalculable disability. This "trivial" disease can be deadly serious.

Measles has been kept successfully under control in the U.S. for decades by the routine administration of MMR vaccination. "MMR" stands for measles, mumps and rubella (sometimes known as German measles). Thanks to the vaccine, introduced in 1963, the incidence of measles in the U.S. has decreased by more than 99 percent and was considered eliminated here in 2000 (meaning that no cases have originated in this country since that year). Prior to the availability of the MMR vaccine an estimated three to four million people in the U.S. were infected each year, with 48,000 needing hospitalization and 4,000 developing encephalitis. An estimated 400-500 people died yearly.

Because the vaccine isn't routinely given elsewhere in the world, we get occasional outbreaks in the U.S. such as the one traced to a young foreign visitor to Disneyland in California in December 2014. According to the U.S. Centers for Disease Control and Prevention (CDC) that single exposure was the primary cause (as of this writing) of 102 cases of measles in 14 states. The CDC also announced that in 2014 a record number of measles cases occurred in the U.S - 644 in 27 states - the most reported since the disease was eliminated in 2000.

Measles has not been eliminated in Europe, where some 30,000 cases have occurred since 2008. In 2013, 15,000 cases and at least six measles deaths occurred in France alone.

There's no treatment for measles other than letting it run its course. Infants with known exposure can receive the MMR within three days to limit the severity of the infection. Pregnant or immune-compromised people can receive serum immune globulin injections, which provide pre-formed antibodies to fight the infection. When given within six days of viral exposure, this treatment can prevent measles or make symptoms less severe.

I definitely believe that children should get the MMR vaccine as recommended - one shot at 12 to 15 months old and the second between ages four and six. I made sure my daughter had all her shots as scheduled.

Parents who decline to have their children vaccinated put both their families and others at risk, often believing (erroneously) that the MMR vaccine is linked to autism. That idea came from a 1998 report in the medical journal The Lancet. However, since then extensive reports from the American Academy of Pediatrics, the Institute of Medicine and the CDC have shown that there is no scientifically proven link between the MMR vaccine and autism.

If you have children who have not been vaccinated against measles, please make sure they get the shots.

Andrew Weil, M.D.

SOURCE:
"Measles History", U.S. Centers for Disease Control and Prevention, accessed February 4, 2015
http://www.cdc.gov/measles/about/history.html

[kepp]

California warns against intentional measles exposures

Yes, people are actually doing this.

[Loneiguana]

Originally Posted by kepp

California warns against intentional measles exposures

Yes, people are actually doing this.

Yup

Parents are having measles parties instead of vaccinating children

http://national.suntimes.com/nationa...easles-parties

If only there was some way to, I don't know, inject a child with a version of the measles that won't get the child sick, but will build up the immune system. Some sort of vaccine or something.


Hey, at least they have literature to help a child deal with having criminally stupid parents.



/yes, that is a real book

[Eleazar]

Originally Posted by kepp

California warns against intentional measles exposures

Yes, people are actually doing this.

[Otter]

Originally Posted by ThaVirus

Don't you want your kids to get chicken pox while they're young?

I remember when our cousins got it our mom made us rub him so we'd get it as well.

Huh, just when I thought my uncle Charlie showing me his uncircumcised penis couldn't get any more awkward.

[Mr. Laz]

Yes u should get vaccines. And so what if that makes your kid artistic. That don't always mean he's gay.

— Luwanda (@LuwandaJenkins) February 3, 2015

[Dave Lane]

Hey I'm artistic, or was that autistic?

[WhawhaWhat]

Originally Posted by Mr. Laz

Yes u should get vaccines. And so what if that makes your kid artistic. That don't always mean he's gay.

— Luwanda (@LuwandaJenkins) February 3, 2015

That's true.

[BigRedChief]

Originally Posted by Mr. Laz

Yes u should get vaccines. And so what if that makes your kid artistic. That don't always mean he's gay.
— Luwanda (@LuwandaJenkins) February 3, 2015

Vaccines make you gay?

[RaiderH8r]

Originally Posted by kepp

California warns against intentional measles exposures

Yes, people are actually doing this.

This is a special brand of stupid. It goes beyond irretrievably stupid and into a realm of heretofore unknown stupidity. They're really pioneers. Trailblazers of their age.

[kepp]

A very compelling article/study: link

Autism in the absence of MMR vaccine
Clinical bottom line
Autism rates in Japan continued to rise after the withdrawal of MMR vaccine.

Reference
H Honda et al. No effect of MMR withdrawal on the incidence of autism: a total population study. Journal of Child Psychology and Psychiatry 2005 doi: 10.1111/j.1469-7610.2005.01425.x
Background
A link has been postulated between the specific use of the triple MMR vaccine and the rise of childhood autism. Though very considerable research has shown there to be no connection, some people continue to believe in such a link and they propose use of single vaccines instead. In Japan, MMR vaccine was introduced in 1989, but the programme was terminated in 1993 and only single vaccines used thereafter.

The experience of Japan therefore constitutes a real-world experiment of replacing triple MMR vaccine with single vaccines because of problems with production. If the proponents of a link between MMR and autism are correct, the result should be that cases of autism fall after withdrawal of MMR.

Study
The study was conducted in a part of Yokohama with a population of about 300,000, and which was stable, or reflected changes typical for Japanese society as a whole, over the period of the study. The population was served by a special centre (Yokohama Rehabilitation Centre) that included a developmental psychiatry unit with early intervention services for developmental disorders. There was in place an early detection and intervention system that included specific routine checkups at four, 18 and 36 months, working to defined diagnostic criteria. At 18 months, about 90% of children participated in the programme, but those who did not, or those who were missed by the programme, could be referred by nurseries, paediatric clinics, or other services. These services began in 1987, two years before introduction of MMR.

Not only did the study have specific diagnostic criteria, therefore, but also ensured a complete coverage of a defined population, consistently over a period covering the introduction and withdrawal of the triple MMR vaccine.

Each birth cohort from 1988 to 1996 was followed up to age seven years, and results presented for all autistic spectrum disorders, for autism, and for autism associated with regression. The cumulative incidence per 10,000 children for each diagnosis was calculated for each year.

Results
Over the whole period, and with full follow up to age seven years in birth cohorts from 1988 to 1996, 278 children developed autistic spectrum disorder, 158 autism, and 120 other autistic spectrum conditions. Of those with autism, 60 had definite regression and another 12 probable regression according to defined tests.

In the 1988 birth cohort, 70% of children had the MMR triple vaccine, falling to 1.8% in the 1992 birth cohort. Thereafter no children had the MMR triple vaccine (Figure 1).

Figure 1: Autistic conditions in birth cohorts to age seven years, and MMR vaccination rate in Japan: autism, all autistic spectrum disorders (ASD), and autism with regression

The incidence of all autistic spectrum disorders, and of autism, continued to rise after MMR vaccine was discontinued. The incidence of autism was higher in children born after 1992 who were not vaccinated with MMR than in children born before 1992 who were vaccinated. The incidence of autism associated with regression was the same during the use of MMR and after it was discontinued.

The increase of autistic spectrum disorders was evident in children with higher IQ.

Comment
The increase in autism and autistic spectrum disorders in this part of Yokohama displays the same increase over time seen in other parts of the world. Here, though, the increase occurred even when the MMR vaccine was withdrawn. This destroys any possible causative link between use of the vaccine and autism.

Perhaps the most important features of the study were that it comprehensively covered a population, and that the population was served by a special service testing children for developmental; disorders and using standard methods over the whole period. The quality and validity of the study is superlative, and the size good.

Whatever causes autism, it is not the MMR vaccine.

[KC native]

I’m an Anti-Braker

Guys, I wanted to let you know about a personal decision I recently made. I don’t really feel like discussing it, but I want to put my position out there. Please be respectful. This is a really long post, but please read the whole thing.

I’m taking the brakes off my car. This isn’t a rash decision, so please listen up.

A few weeks ago I saw a car accident - two people went through an intersection at the same time. Both slammed on their brakes at the same time and collided. Fortunately no one was seriously injured.

But then it occurred to me - if they had just gone through the intersection, they wouldn’t have collided. The brakes CAUSED the accident!

So, I decided to do my own research and what I found was *staggering*: Hundreds of people every year are seriously injured by unnecessary braking. One time, I was driving in the snow and I just lightly tapped my brakes and it caused my car to COMPLETELY LOSE CONTROL. My brakes could have very easily gotten me killed. Even more astoundingly is how often brake pads will warp and distort rotors, causing bumpy rides and squeaky wheels.

And you know what? I also found that decades ago brakes weren’t even used! People would control their vehicle’s speed with downshifting and engine braking. Maybe it’s just coincidence, but back when engine braking was used there were almost no automotive fatalities. There were NEVER brake caused car accidents.

After doing some more digging, I found a nefarious plot - Mechanics: The very people who we trust to work on and care for our cars - get PAID to install and change brakes! You might THINK they care about our safety, or our cars - but they’re just in it for the $49.99 brake pad installations.

So I talked to my Mechanic about taking the brakes off my car and I was disgusted by how poorly he treated me. He accused me of being ignorant, when I was the one that looked up how much rotational torque brakes can put on your rotors. He didn’t even know how much torque a rotor can take before being warped!!! He said “rotors are designed to be compressed, that it isn’t actually a problem” just completely dismissing me.

Then he had the NERVE to say that my personal choice had consequences, that I would affect everyone around me. Well I’ve had it with him, I’m looking for a new mechanic. The problem is that so many mechanics are bought and paid by the automotive industry that ALL of them are insistent about my car having brakes. Most of them won’t even look at my car for other reasons, saying that a brakeless car could cause damage to their shop and other cars. What a bunch of bullshit, they just don’t like those who believe in alternative braking techniques.

Now of course big government is getting involved, saying that I *MUST* have brakes. That this isn’t just about me, and that I could hurt people. What happened to personal freedom? What happened to liberty?

So all I’m saying is, do your research. Don’t just listen to the NTSB and big automotive. I made a personal decision for my family, we just said no to brakes. We’ll be using natural remedies like Gravity, and putting our feet on the ground to stop. After all, if that was good enough for me when I was on my bike as a kid, it’s good enough for my children in my car.

Please keep the comments respectful!

Legal Disclaimer: I am not a mechanic and should not be considered a valid source of information for automotive inquiries.

Perfect mockery of the antivaccine idiots.

http://robertmoorejr.tumblr.com/post...an-anti-braker