The thing I think may harm the MCU's longterm profit margin are the Disney series with Loki, WandaVision, and Falcon/Bucky.
With those shows ongoing featuring central characters, the maintenance of having to keep up with the MCU is going to increase. I think one of the reasons the MCU has thrived is because they come out basically twice a year, which (a.) forces fans to wait, but more importantly (b.) makes keeping up with the MCU low-effort.
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