To be fair, most of Spider-Man's major villains were created in the 60's, when comic book characters weren't exactly nuanced. On the other hand, that same decade gave us Loki, Galactus, Kingpin, Magneto, Juggernaut, Mandarin, Ultron, and Dr. Doom. So, yeah, for being the story of a science wunderkind, Spider-Man is unusually anti-science in this regard.
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