I've heard so many bug stories about he Ryujin quest that I just never bother with it. Sometimes the only winning move is not to play.
As for the game, I'm still at it. Up to level 151, getting ready to finish up NG2. I still haven't run across as many bugs this time, although it is starting to get a little wonkier as I progress. The most pervasive one is Andreja's head going into stealth mode whenever I do a sales run at Neon. You'd think the NPCs would comment about the headless woman following me around, but they don't seem to.
A couple of things I've learned this playthrough:
1. I finally decided not to rat out Vae Victus for the Londinium thing. If you do that, you get all the same rewards and nobody figures it out, and after that you can visit him in his cell and he'll give you assassination missions. There's nothing really special or different about them (still attacking pirates in the same old bases on random planets), but the ultimate target will be identified as something like "chem cooker" or "intelligence asset."
2. At long last, I know the one and only use for the mysterious "quark degenerate tissues." If you complete level 4 of gastronomy, which I only did to complete all the research, you can cook a level 4 dish which uses it as an ingredient that gives you massive defensive bonuses. I wouldn't say it's worth the trouble of getting to level 4 - I must have spent the better part of two hours wandering from vendor to vendor looking for large amounts of ****ing butter and eggs at one point - but there is a decent payoff at the end. Makes me wish I hadn't sold off so many of them, because they did eventually prove to be useful.
And one really cool thing I discovered I could to is completely enclose the ship cockpit (saw it in a YouTube video), which has enabled me to construct the coolest ship design I've done so far. All the weapons and the shield are glitched in, so the top of the ship is completely sleek. The only downside is the cockpit has no exterior view from the inside, but it doesn't matter when flying around because I always use the default full ship/third person view anyway. I'll attach a couple of images in a spoiler since they're pretty big.
Oh, another thing I forgot to mention was an annoying maybe glitch/maybe **** you to hijackers issue with advancing the ship command skill. You have to destroy or board enemy ships in order to level up, but you have to use a ship you've either bought from a ship vendor or been given (Frontier, Razorleaf, Star Eagle) or your kills/captures don't count toward advancement. I also found out the hard way that selling a captured ship and then buying it back from the merchant (basically laundering it) doesn't work. Apparently to Bethesda, once hijacked, always hijacked. That cost me about half a million credits. ****ers. Luckily, the ship in the above images was once the Frontier, even though no original parts remain, so her kills count.