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Old 08-13-2018, 09:17 PM   #56
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Quote:
Originally Posted by BIG_DADDY View Post
What she said about doing the blood test to see what your food allergies are is really important as I mentioned earlier. There is actually another way to do it but it is most likely unavailable there. What she said about tumeric is right on the money. I use the curcumin extract powder that I buy in bulk and mix with broth. If you do that and eat red or black cherries you will notice within a few days the difference. I have it in my hands as well from years of lifting and martial arts
You might be referencing some older information that has since been proven false. Not trying to be a jerk. But the most recent meta-study on tumeric/curcumin looks at >120 different scientific studies and includes 164 references. Please take a look at the meta-study below in the link and the included references if you're curious. Here's the result:

Quote:
Curcumin has recently been classified as both a PAINS (pan-assay interference compounds) and an IMPS (invalid metabolic panaceas) candidate. The likely false activity of curcumin in vitro and in vivo has resulted in >120 clinical trials of curcuminoids against several diseases. No double-blinded, placebo controlled clinical trial of curcumin has been successful. This manuscript reviews the essential medicinal chemistry of curcumin and provides evidence that curcumin is an unstable, reactive, nonbioavailable compound and, therefore, a highly improbable lead.

[...]

At first, curcumin appeared to offer great potential for the development of a therapeutic from a NP (turmeric) that is classified as a GRAS material. Unfortunately, no form of curcumin, or its closely related analogues, appears to possess the properties required for a good drug candidate (chemical stability, high water solubility, potent and selective target activity, high bioavailability, broad tissue distribution, stable metabolism, and low toxicity). The in vitro interference properties of curcumin do, however, offer many traps that can trick unprepared researchers into misinterpreting the results of their investigations.

[...]

With respect to curcumin/curcuminoids and in vivo studies and clinical trials, we believe there is rather “much ado about nothing”. Certainly, the low systemic exposure levels reported in clinical trials do not support its further investigation as a therapeutic. Circumventing the requirement for systemic circulation, curcumin might provide benefit by acting on gut microbiota. Thus far, there is limited evidence to support this hypothesis, which will also limit the utility of this delivery method. Delivery systems such as lipid vesicles, nanoparticles, and nanofibers might be able to boost the bioavailability of 1, but this could also conceivably narrow its therapeutic window and lead to off-target toxicity by aforementioned processes. Available evidence demonstrates curcumin will ultimately degrade upon release into physiologic media, no matter the delivery mechanism. Analogues of 1 might address some of the delivery challenges but would be new chemical entities and would have to proceed through expensive preclinical work to be approved for clinical trials. In our opinion, analogues of curcumin are based on a fairly weak foundation.

https://pubs.acs.org/doi/pdf/10.1021...edchem.6b00975
Again, I'm not trying to be a dick. Just offering what I've found to be the most recent scientific information about the subject. If you have more recent contradictory studies/information, I'd gladly refer to that, feel free to offer it up.
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