Marcellus |
05-21-2018 01:12 PM |
Quote:
Originally Posted by scho63
(Post 13563902)
WOW :eek::eek::eek:
I hope it wasn't passed to the next generation
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It has and will continue to be unfortunately, at least for a few more generations.
You can be a defect carrier and never get symptoms yourself (kidney disease) and then pass it on.
Since its an X chromosome defect and Girls = XX and Boys = XY, males always determine gender.
If you are female and are a carrier you have a 50% chance of passing it along to your offspring, it depends on which X chromosome you pass to your kid, the good one or the bad one. If you are male and are a carrier if you have a girl well, you passed it on since you only have one X chromosome to give.
My grandfather who died from it had 6 daughters so they all ended up with it either symptomatic or as a carrier. 3 daughters were symptomatic, 3 were just carriers. 2 of my aunts who were asymptomatic passed it on to their sons who developed Kidney disease and had transplants. That's shit luck. The 3 symptomatic daughters all died from it.
Fortunately for me and my 2 brothers it appears all 3 of us dodged the bullet with our mom not passing the defective X chromosome to any of us as far as we can tell. My daughter has been genetically tested and she isn't a carrier so no way am I a carrier. My brothers only have 1 boy between them so its possible they are carriers but neither are symptomatic and it usually manifests itself by your 20's if you will be. So they wont be passing it on fortunately.
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